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KMID : 0367419770180060029
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Journal of Korean Pediatric Society
1977 Volume.18 No. 6 p.29 ~ p.38
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Clinical Studies on Typhoid Fever in Children
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朴洪錫/Park, Kee Surk
金周龍/朴鍾茂/Kim, Joo Ryong/Park, Chong Moo
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Abstract
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During the last 2 years and 6 months which was from May, 1972 to November, 1974, 120 cases of typhoid fever were admitted to the Department of Pediatrics, Hanyang University Hospital, and evaluated clinically.
Following could be summarized.
1) The seasonal incidence was prominent in July to September (60.896). It was more common in boy than girl, 60.8% and 39.2%. The peak age group was from 6 to 10 years old (52.2%) and the youngest case was 1 year and 2 months old boy. The 85.0% of cases were admitted within less than 2 weeks after onset of the illness.
2) The chief complaints on admission were fever (96.4%), nausea and vomiting (35.8%), abdominal pain (35.096), headache (20.0%), diarrhea (17.6%), and anorexia (14.2%). On the physical examination, fever(90.0%), hepatomegaly(6& 3%), abdominal tendemess(37.7%), coated tongue (29.6%), and splenomegaly (15.0%) were noted. The rose spots were found in only 3 cases (2.5%), and relative bradycardia could be seen more markedly in above 8 years of age.
3) Laboratory findings were as follows;
Leukopenia was 33.3% and absolute leukopenia 4.296 only. Anemia was present in 25.8%, however, there were no any cases of which Hb. level is less than 8gm%. The positive bacteriologic cultures were low in incidence, which were 26.7% of blood, 15.7% of stool. Widal test was positive in 74.2% of the cases and the incidence of positive tests were increased rapidly from the 2nd week of the illness. The positive Widal test was higher in nontreated group than treated group before admission, and vaccinated group than nonvaccinated group.
4) The period required for defervescence war 4.3 daYR with ampicillin only, 4.2 days with C-M only, 3.8 days with ampicillin and C-M, 3.5 days with ampicillin and Bactrim, 3.3 days with C-M and Bactrim, and 4 days with Bactrim only. The associated diseases were meningitis, pneumonia, tonsillitis, and hepatitis.
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